Biological approaches toward dental pulp regeneration by tissue engineering

Tissue Engineering Considerations in Dental Pulp Regeneration

Regenerative endodontic procedure is introduced as a biologically based treatment for immature teeth with pulp necrosis. Successful clinical and radiographic outcomes following regenerative procedures have been reported in landmark case reports. Retrospective studies have shown that this conservative treatment allows for continued root development and increases success and survival rate of the ...

tissue engineering considerations in dental pulp regeneration

regenerative endodontic procedure is introduced as a biologically based treatment for immature teeth with pulp necrosis. successful clinical and radiographic outcomes following regenerative procedures have been reported in landmark case reports. retrospective studies have shown that this conservative treatment allows for continued root development and increases success and survival rate of the ...

Dental pulp tissue engineering.

Dental pulp is a highly specialized mesenchymal tissue that has a limited regeneration capacity due to anatomical arrangement and post-mitotic nature of odontoblastic cells. Entire pulp amputation followed by pulp space disinfection and filling with an artificial material cause loss of a significant amount of dentin leaving as life-lasting sequelae a non-vital and weakened tooth. However, regen...

Gene-enhanced tissue engineering for dental hard tissue regeneration: (2) dentin-pulp and periodontal regeneration

Potential applications for gene-based tissue engineering therapies in the oral and maxillofacial complex include the delivery of growth factors for periodontal regeneration, pulp capping/dentin regeneration, and bone grafting of large osseous defects in dental and craniofacial reconstruction. Part 1 reviewed the principals of gene-enhanced tissue engineering and the techniques of introducing DN...

Pulp Regeneration by Harnessing Dental Pulp Stem Cells